Improving Sperm Quality: 10 Things That Harm Your Sperm Quality

Dr. Natalie Crawford, explains the top 10 things that can impact sperm quality. So often we talk about female factors and egg quality, but the semen analysis is a crucial piece in an infertility evaluation. 40% of infertility is caused or contributed by male factor.

Questions Answered:
What is a semen analysis?
What is the life cycle of sperm?
How does smoking cigarettes impact sperm?
Does alcohol have a negative impact on sperm quality?
What affect does marijuana usage have on sperm?
What environmental toxins impact sperm?
How do weight and diet play a role in sperm quality?
Can illness impact sperm quality?
How does age impact sperm quality?
Does steroid use impact sperm?

Resources:
Maldonado-Cárceles AB, Mínguez-Alarcón L, Mendiola J, Vioque J, Jørgensen N, Árense-Gonzalo JJ, Torres-Cantero AM, Chavarro JE. Meat intake in relation to semen quality and reproductive hormone levels among young men in Spain. Br J Nutr. 2019 Feb;121(4):451-460. doi: 10.1017/S0007114518003458. PMID: 30560757; PMCID: PMC6375748.

du Fossé NA, van der Hoorn MP, van Lith JMM, le Cessie S, Lashley EELO. Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis. Hum Reprod Update. 2020 Sep 1;26(5):650-669. doi: 10.1093/humupd/dmaa010. PMID: 32358607; PMCID: PMC7456349.

Finelli R, Mottola F, Agarwal A. Impact of Alcohol Consumption on Male Fertility Potential: A Narrative Review. Int J Environ Res Public Health. 2021 Dec 29;19(1):328. doi: 10.3390/ijerph19010328. PMID: 35010587; PMCID: PMC8751073.

Tang Q, Pan F, Wu X, Nichols CE, Wang X, Xia Y, London SJ, Wu W. Semen quality and cigarette smoking in a cohort of healthy fertile men. Environ Epidemiol. 2019 Aug 13;3(4):e055. doi: 10.1097/EE9.0000000000000055. PMID: 31538136; PMCID: PMC6693933.

Palmer NO, Bakos HW, Fullston T, Lane M. Impact of obesity on male fertility, sperm function and molecular composition. Spermatogenesis. 2012 Oct 1;2(4):253-263. doi: 10.4161/spmg.21362. PMID: 23248766; PMCID: PMC3521747.

Payne KS, Mazur DJ, Hotaling JM, Pastuszak AW. Cannabis and Male Fertility: A Systematic Review. J Urol. 2019 Oct;202(4):674-681. doi: 10.1097/JU.0000000000000248. Epub 2019 Sep 6. PMID: 30916627; PMCID: PMC7385722.

Ferramosca A, Zara V. Diet and Male Fertility: The Impact of Nutrients and Antioxidants on Sperm Energetic Metabolism. Int J Mol Sci. 2022 Feb 25;23(5):2542. doi: 10.3390/ijms23052542. PMID: 35269682; PMCID: PMC8910394.

Salas-Huetos A, Bulló M, Salas-Salvadó J. Dietary patterns, foods and nutrients in male fertility parameters and fecundability: a systematic review of observational studies. Hum Reprod Update. 2017 Jul 1;23(4):371-389. doi: 10.1093/humupd/dmx006. PMID: 28333357.

Mima M, Greenwald D, Ohlander S. Environmental Toxins and Male Fertility. Curr Urol Rep. 2018 May 17;19(7):50. doi: 10.1007/s11934-018-0804-1. PMID: 29774504.

Shahat AM, Rizzoto G, Kastelic JP. Amelioration of heat stress-induced damage to testes and sperm quality. Theriogenology. 2020 Dec;158:84-96. doi: 10.1016/j.theriogenology.2020.08.034. Epub 2020 Sep 8. PMID: 32947064.

Hajizadeh Maleki B, Tartibian B. COVID-19 and male reproductive function: a prospective, longitudinal cohort study. Reproduction. 2021 Mar;161(3):319-331. doi: 10.1530/REP-20-0382. PMID: 33522983.

Wang S, Zhang A, Pan Y, Liu L, Niu S, Zhang F, Liu X. Association between COVID-19 and Male Fertility: Systematic Review and Meta-Analysis of Observational Studies. World J Mens Health. 2023 Apr;41(2):311-329. doi: 10.5534/wjmh.220091. Epub 2022 Oct 4. PMID: 36326165; PMCID: PMC10042646.

Liu X, Wang Z, Liu F. Chronic exposure of BPA impairs male germ cell proliferation and induces lower sperm quality in male mice. Chemosphere. 2021 Jan;262:127880. doi: 10.1016/j.chemosphere.2020.127880. Epub 2020 Aug 5. PMID: 32777607.

Cessation of chronic delta-9-tetrahydrocannabinol use partially reverses impacts on male fertility and the sperm epigenome in rhesus macaques. https://www.fertstert.org/article/S0015-0282%2823%2900167-X/fulltext