Thin Endometrial Lining
Dr. Natalie Crawford discusses what it means to have a thin endometrial lining. A thin lining typically is something noticed in IVF or embryo transfers as well as ovulation induction and IUI cycles. She goes over what can cause a thin endometrial lining and what can be done to fix it.
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Natalie answers your social media questions during her segment FFS—For Fertility’s Sake.
Can you get pregnant with one Fallopian tube?
Is an ERA worth it?
Can hypothyroidism impact my ability to have a baby?
My luteal phase is 10 days but my progesterone levels are normal. Is this okay?
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Resources:
Liu KE, Hartman M, Hartman A, Luo ZC, Mahutte N. The impact of a thin endometrial lining on fresh and frozen-thaw IVF outcomes: an analysis of over 40 000 embryo transfers. Hum Reprod. 2018 Oct 1;33(10):1883-1888. doi: 10.1093/humrep/dey281. PMID: 30239738; PMCID: PMC6145412.
Zhang T, Li Z, Ren X, Huang B, Zhu G, Yang W, Jin L. Endometrial thickness as a predictor of the reproductive outcomes in fresh and frozen embryo transfer cycles: A retrospective cohort study of 1512 IVF cycles with morphologically good-quality blastocyst. Medicine (Baltimore). 2018 Jan;97(4):e9689. doi: 10.1097/MD.0000000000009689. PMID: 29369190; PMCID: PMC5794374.
Mahutte N, Hartman M, Meng L, Lanes A, Luo ZC, Liu KE. Optimal endometrial thickness in fresh and frozen-thaw in vitro fertilization cycles: an analysis of live birth rates from 96,000 autologous embryo transfers. Fertil Steril. 2022 Apr;117(4):792-800. doi: 10.1016/j.fertnstert.2021.12.025. Epub 2022 Jan 31. PMID: 35109980.
Li X, Luan T, Zhao C, Zhang M, Dong L, Su Y, Ling X. Effect of sildenafil citrate on treatment of infertility in women with a thin endometrium: a systematic review and meta-analysis. J Int Med Res. 2020 Nov;48(11):300060520969584. doi: 10.1177/0300060520969584. PMID: 33176524; PMCID: PMC7673063.
Management of thin endometrium in assisted reproduction: a clinical practice guideline from the Canadian Fertility and Andrology Society
Shakerian B, Turkgeldi E, Yildiz S, Keles I, Ata B. Endometrial thickness is not predictive for live birth after embryo transfer, even without a cutoff. Fertil Steril. 2021 Jul;116(1):130-137. doi: 10.1016/j.fertnstert.2021.02.041. Epub 2021 Mar 31. PMID: 33812651.
