AMH: How Can Low AMH Impact Fertility? What Should You Know About AMH?

Double board certified OBGYN and REI, Dr. Natalie Crawford, discusses AMH, what you should know, and how it can impact your fertility.

Questions Answered:
What is AMH?
How is it tested?
When does the process of egg loss begin?
How do you test egg quantity?
Does your AMH fluctuate?
What causes chromosomal abnormality?
How is AMH impacted by hormonal contraception?
What can decrease AMH?When should you get your AMH checked?
What can help egg quality?

Resources:
Steiner AZ, Jukic AM. Impact of female age and nulligravidity on fecundity in an older reproductive age cohort. Fertil Steril. 2016;105(6):1584–1588.

Steiner AZ, Pritchard D, Stanczyk FZ, et al. Association Between Biomarkers of Ovarian Reserve and Infertility Among Older Women of Reproductive Age. JAMA. 2017;318(14):1367–1376.

Mesen TB, Mersereau JE, Kane JB, Steiner AZ. Optimal timing for elective egg freezing. Fertil Steril. 2015;103(6):1551–6.

Fritz and Speroff, Clinical Gynecology Endocrinology and Infertility, 8th edition, 2011

Ligon S, Lustik M, Levy G, Pier B. Low antimüllerian hormone (AMH) is associated with decreased live birth after in vitro fertilization when follicle-stimulating hormone and AMH are discordant. Fertil Steril. 2019 Jul;112(1):73-81.e1.

Seyhan A, Ata B, Uncu G. The Impact of Endometriosis and Its Treatment on Ovarian Reserve. Semin Reprod Med. 2015 Nov;33(6):422-8. doi: 10.1055/s-0035-1567820. Epub 2015 Nov 23.

Landersoe SK, Birch Petersen K, Sørensen AL, Larsen EC, Martinussen T, Lunding SA, Kroman MS, Nielsen HS, Nyboe Andersen A. Ovarian reserve markers after discontinuing long-term use of combined oral contraceptives. Reprod Biomed Online. 2020 Jan;40(1):176-186.

Porcu E, Cillo GM, Cipriani L, Sacilotto F, Notarangelo L, Damiano G, Dirodi M, Roncarati I. Impact of BRCA1 and BRCA2 mutations on ovarian reserve and fertility preservation outcomes in young women with breast cancer. J Assist Reprod Genet. 2020 Mar;37(3):709-715. doi: 10.1007/s10815-019-01658-9. Epub 2019 Dec 24.

Bedenk J, Vrtačnik-Bokal E, Virant-Klun I. The role of anti-Müllerian hormone (AMH) in ovarian disease and infertility. J Assist Reprod Genet. 2020 Jan;37(1):89-100. doi: 10.1007/s10815-019-01622-7. Epub 2019 Nov 21. PMID: 31755000;

Berjeb KK, Debbabi L, Braham M, Zemni Z, Chtourou S, Hannachi H, Hamdoun M, Ayadi M, Kacem K, Zhioua F, Fadhlaoui A, Bahri O, Chakroun N. Evaluation of ovarian reserve before and after chemotherapy. J Gynecol Obstet Hum Reprod. 2021 May;50(5):102035

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